Bio-pharmaceuticals refers to the manufacture of products from organ↔isms, biological tissues, cells and body fluids, etc. by compreheλnsive utilization of the research results, scientific principles and ♣methods of microbiology, biology, medical science, chemistry, biochemistrφy, biotechnology, pharmacy and so on, for disease prevention, treatment and diagnos↑is purposes.
China's biopharmaceutical industry is facing a favorable development environmen£t. In recent years, with continuous transformation and upgrading of βChinese domestic biopharmaceutical industry, and with the enhancement of the R&D inv∞estment, production capacity and industry concentration, the overall technical level of China&φ#39;s biopharmaceutical industry has been significantly improved, which provi>des a strong foundation for biopharmaceutical research and development.
With the progress of the preliminary stage R&D level of biopharm∑aceutical industry, higher requirements have been placed on the corres×ponding time, efficiency and cost of the R&D. In order to inve∞st less in the preliminary stage and have a short R&D time, the research and' the production of micro-level raw materials in the preliminary stag™e need the corresponding high-level extraction equipment for clarification, purificatiλon and concentration purposes, which brings difficulties for the developmentδ of the industry, especially for some new technologieφs, such as membrane separation and purification technology, electrodialysis technology and₹ so on.
The current membrane separation and purification equipment can not be ♥used in the micro-level product and process R&D in the biopharma©ceutical industry. As a result, companies and research institutions have to increa se the amount of research products, or are forced to enlarge the amount of research products. If the amount of research product canno€t be enlarged during R&D period, it means that• new technologies and processes have to be given up. This makes the research of the ★extraction technology and process in biopharmaceutical industry face an embarrassing situation t hat whether they have to keep backward or they are unable to utilize certain extraction technology≈ and process.
In terms of membrane separation and purification, if the correspo"nding membrane equipment can be used for the micro-level product and process ★R&D, then the difficult problem for preparation of micro-level raw materi↑als for biopharmaceutical industry will be solved, which is also the problem t hat the relevant enterprises and research institut≠ions are eager to solve. At present, the minimum fee>d rate of membrane separation equipment on the market is 2>L or more. If the feed rate is lower than this, the experimental equipment may ¥be unable to work or the experimental data may not be accurate. Howev er, the raw material amount required by the preliminary R&D sπtage in biopharmaceutical industry is generally 200ML~1"L, or even less, which leads to the problems mentioned above.
In order to solve the problem of preparing micro-lev™el raw materials for the preliminary R&D stage in biopharmaceutical indus©try, Guo Chu Technology (Xiamen) Co., Ltd., based on its advantage and experienceπ, has developed Micro-Scale Tangential-Flow Experimental Device specially for universities, ✔scientific research institutions and enterprise laboratories. The device can work with very little feed amount and the minimum circulation volume is &only 50ml, which is mainly used for laboratory experiments for micro-level raw material sepa'ration, purification, concentration and extraction, such as: separation and purification of÷ micro-level raw water, cell separation and purificat>ion, protein separation and purification, polysaccharide separation and pγurification, sugar alcohol separation and purification, component concentration desalination, antibiotic separation and purification, anti-tumor drug™ separation and purification, animal extract separatio∞n and purification, plant extract separation and purification, fermentation &broth separation and purification, amino acid separation and purification, enzyme ↕separation and purification.
It is reported that the device has been adopted by many membrane R&D institutioΩns, mainly used for testing the performance of microfiltration membrane©, ultrafiltration membrane, nanofiltration membrane, reverse osmosis memb∑rane, modified membrane, or for membrane flux test, membrane→ rejection rate test, membrane solvent resistance test, meβmbrane alkali resistance test, membrane acid resistance test, membrane temperature resistance te£st, membrane recovery test after membrane cleaning, membrane anti-pollution te≈st, membrane integrity test and so on.
Guo Chu Technology (Xiamen) Co., Ltd. now has strategic cooperation with many global membranγe manufacturing giants. It can provide membrane mater∏ials with full range of precision covering microfiltration, ultrafiltration, nanofγiltration and reverse osmosis, which can achieve selective separation under the condition that the feed liquid amount in the laboratory is very small, which h&as been regarded as a sharp weapon for the preliminary lab R&D for biopharmaceutical products, which can also realize the function of ‘ one machine with multiple purposes’.
